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한국생활환경학회|한국생활환경학회지 2020년 8월

기사명 중년 남성의 흡연습관과 신체활동이 백혈구 텔로미어 길이에 미치는 영향 / The Effect of Smoking Habits and Physical Activity on Leukocyte Telomere Length in Middle Aged Men
저자명 신윤아 ; 박동호 ; 김창선
발행사 한국생활환경학회
수록사항 한국생활환경학회지 , Vol.27 No.4(2020-08)
페이지 시작페이지(489) 총페이지(9)
ISSN 12261289
주제분류 환경및설비
주제어 ; Smoking habite; physical activity; inflammation; oxdiative stress; telomere length
요약2 This study was to investigate the effects of smoking habits and physical activity on telomere length in middle aged men. This study was conducted on 106 middle aged men. We examined smoking habites such as smoking period and amount per week, physical activity inflammation markers including c-reactive protein (CRP) and lactate dehycrogenase (LDH), oxidative stress marker (8-OHG), and telomere length. Waist circumference were significant difference between smoking and non-smoking groups (p<.05). Physical activity (PA) were not difference between smoking and non-smoking groups. LDH levels significant difference between smoking and non-smoking groups (p<.05).
High-intensity PA has shown a negative association with LDH levels (r=-.117, p<.05) and 8-OHdG (r=-.234, p<.05).
Moderate-intensity PA frequency has shown a negative association with 8-OHdG (r=-.223, p<.05). Telomere length has shown a negative association with smoking period (r=-.340, p<.05) and LDH levels (r=-.239, p<.01). These results suggested that smoking and PA affected inflammation and oxidative stress, but did not affect telomere because it was not clinically meaningful. Therefore, it is considered that further research is needed to analyze the chnages according to observation at various time points in the long period.
소장처 한국생활환경학회
언어 한국어
DOI http://dx.doi.org/10.21086/ksles.2020.02.27.4.489